Role of Type VI Secretion System during shrimp infection of Vibrio spp.-causing acute hepatopancreatic necrosis disease (AHPND)
This project will investigate the potential role of Type VI Secretion System encoded by Vibrio-causing AHPND during shrimp infection. It has been shown that AHPND is caused by plasmid-encoded binary toxins V. parahaemolyticus Photorhabdus insect-related toxins (PirAVP and PirBVP). However, little is known about the pathogenicity and it remains unknown whether other virulent factors are …